1980 Volume 21 Issue 10 Pages 1295-1303
The outbreak of hepatitis A occurred in a junior high school of Ghodo town, located in the rural district of Ogaki city. The clinical course and time change of abnormal laboratory data of fifty patients who admitted to Ogaki municipal hospital and two other hospitals in the town were reported.
Fever, nausea and general fatigue disappeared within a week in almost all patients. Hepatomegaly continued over three months in 25%. The duration of abnormal S-GOT, S-GPT and IgM was longest in icteric group.
The laboratory recovery needed more days in the group, which γ-GTP was high at onset of the illness. Recovery of total bilirubin, S-GPT and IgM was delayed in the group which TTT elevated for many months or re-elevated. TTT seems to be a good indicator for prolongation of this illness.
The time change of anti HA titer showed biphasic curve and the two peaks were observed at 2 week and 6 month after onset of the illness. Initial peak coincidates with that of IgM.
Reelevation of transaminase and gradual elevation of total bilirubin were observed in 4 and 2 cases respectively.
