1980 Volume 21 Issue 10 Pages 1385-1389
43-year-old man of hepatocellular carcinoma with bone metastases, especially to the skull was reported. There was no previous history of liver disease. He complained of severe headache, lumbago, back pain, leg pain, and right hypochondralgia. Liver function tests showed slight increase of alkaline phosphatase, γ-GTP, GOT and GPT and prominent decrease of cholinesterase. In serological tests, HBs antigen and HBs antibody were negative. The levels of alphafetoprotein and CEA were within normal. In radiology, many osteolytic areas were demonstrated. The present study indicates the multiplicity of syndrom in patient with hepatocellular carcinoma.
