Abstract
A 65 ycar-old female was suspected as chronic hepatitis and received therapy a few years ago. On admission no particular symptom was fbund. Pruritus and jaundice were not observed.
Laboratory examination showed as fbllows: Total cholesterol 260 mg/dl; total bilirubin 0.5mg/dl; γ-globulin 2.39/dl; IgG 2960 mgldl; IgM 540 mg/dl; ICG (retention rate after 15 min.)7%; HBs antigen(-); HBs an tibody(+); GOT 49 U; GPT 21 U; γ-GTP 120.0μU/ml; LAP 856 U; Al-Pase 28.9 K.A. U.; RA-test(+); serum copper 205 μg/dl; anti-nuclear antibody(+); antimitochondrial antibody(+); anti-smooth muscle antibody (+). Liver scintigram showed no particular findings. The endoscopic retrograde cholangiography revealed no biliary obstruction. No varix was found on gastro-camera examination in the stomach and esophagus. Surgical liver wedge biopsy specimen showed so called chronic nonsuppurative destructive cholangitis, described by Rubin
From these results the case was corresponding to asymptomatic primary biliary cirrhosis reported by Fox et al.
