Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
Assessment of chemotherapeutic effects on hepatocellular carcinoma with special reference to changes of angiographic findings
Kenji HIRAIMasanobu KUMAGAITamotsu SUKOTaisuke SAKEMIYoshikazu NAGASAKIYasuhiko KUBOKyuichi TANIKAWA
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1983 Volume 24 Issue 6 Pages 648-653

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Abstract

The changes of angiographic findings such as tumor size, diameter of the proper hepatic artery (PHA), displacement of the artery, A-V shunt, intrahepatic metastatic lesions, hypervascularity and tumor stain were assessed before and after one-shot injection of anticancer agents via the hepatic artery in 55 cases of unresectable hepatocellular carcinoma (HCC).
The results were shown as follows:
1) A high correlation was noted between the caliber of the PHA and the change in tumor size.
2) Typical angiographic findings of HCC such as hypervascularity, tumor stain, displacement, A-V shunt and metastatic lesions were also changed with tumor size.
3) Angiographic changes did not show to be correlated with tumor effects in aggravated cases after chemotherapy. The caliber of PHA decreased or unchanged in 30%, and the degree of hypervascularity or tumor stain unchanged in 90% cases in spite of tumor enlargement.
These findings described above suggest that in some cases, histological changes after chemotherapy can be assessed on angiography.

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© The Japan Society of Hepatology
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