Abstract
A 21-year-old female patient with type A fulminant hepatitis cured with plasma exchange (PE) is reported. The patient was admitted to our hospital because of hepatic coma (Adams & Foley grade III), oliguria and subcutaneous bleeding in April 1983. Her total bilirubin was 10.lmg/dl, GOT 1, 005IU, GPT 2, 075IU, blood NH3 110μg/dl, total protein 5.9g/dl, BUN 44mg/dl, creatinine 6.4mg/dl, and IgM type anti-HA was demonstrated by HAVAB-M kit. Treatment included prednisolone, glucagon-insulin, heparin, l-DOPA and lactulose. In addition, PE was started on the lst hospital day, and three PEs resulted in her waking from hepatic coma and in disappearance of DIC and renal failure.
A case of type A fulminant hepatitis is rare and five cases in Japan are reviewed.
