Abstract
ICG Rmax was examined in forty-one patients with liver cirrhosis (31 cases) and other diseases (10 cases) from December, 1980 to February, 1982, and abnormal levels of ICG Rmax were obtained in many cases. Accordingly, ICG plasma disappearance curves in ten patients with liver cirrhosis were analyzed pharmacokinetically, and the application of Michaelis-Menten kinetics to the maximum removal rate of ICG (ICG Rmax) was reevaluated. In addition, the method of examination of ICG Rmax which is now widely used was discussed. It was suggested that ICG Rmax could not correctly reflect the functional capacity of the liver.
