1987 Volume 28 Issue 3 Pages 359-362
A 24-year-old female suffered from Primary biliary cirrhosis (PBC) after delivery is reported. She was admitted to Toyokawa City Hospital following general fatigue and abdominal pain. The laboratory data reported a high level of serum ALP, LAP, γ-GTP and IgM. Antimitochondrial antibody was positive. Histological findings of liver biopsy indicated infiltration of lymphocytes and epithelioid cells and the bile duct epithelium with degeneration and disappearance in the portal area. Therefore we diagnosed PBC. Oral administration of predonisolone (20mg/day) brought her marked improvement of laboratory data. The cases in association with PBC, pregnancy and delivery have been rarely reported. Recently it is said the young patients of PBC are increasing, so it is important to investigate the infuluence of pregnancy and delivery on PBC.
