1987 Volume 28 Issue 3 Pages 363-368
A case of sclerosing hepatic carcinoma with a long-term preoperative elevated α-fetoprotein showing good postoperative course was reported. She was a 57 year-old woman who had no complaints and no abnormalities of the liver function tests except a remarkably elevatedα-fetoprotein of 10, 140ng/ml. During the 2 year observation, no tumors producingα-fetoproteins had been recognized. The tumor was found in the left lateral lobe of the liver on ultrasonography and CT-scan after 2 years observation. She was recieved the operation of left lobectomy of the liver Dec 3rd, 1982.
The pathological findings revealed the caracteristics of the sclerosing hepatic carcinoma (SHC), acampanying, in parts, the lamellar fashion of fibrosis, so-called fibrolamellar carcinoma. This case looked different from SHC in some points, eg without pseudohyperparathyroidism, with good clinical course by far over 3 years after lobectomy.
It is likely that the lamellar fashion of fibrosis may be checked the growth and progress of the SHC.