Kanzo
Online ISSN : 1881-3593
Print ISSN : 0451-4203
ISSN-L : 0451-4203
Detection of Pre-S1, S2 peptides in plasma derived vaccine
Yoshimi ITOMasao OMATAOsamu YOKOSUKANaoko HAYASHIMasao OHTO
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JOURNAL FREE ACCESS

1988 Volume 29 Issue 9 Pages 1165-1170

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Abstract

We studied Pre-S1/S2 peptides in different hepatitis B vaccines and their productivity of antibodies against Pre-S1/S2 peptides by immunoblotting method.
We found relatively large amount of Pre-S1/S2 peptides in one plasma derived HB vaccine, not in another two plasma derived HB vaccines and in one HB vaccine from recombinant yeast.
Antibodies for Pre-S1/S2 were found in 23.6% of individuals who were vaccined with Pre-S1/S2 peptides positive vaccine, and positive for anti-HBs antibody.
These data suggested that some plasma derived vaccines had the productivity of antibodies for Pre-S1/S2.

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© The Japan Society of Hepatology
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