Abstract
The author examined the effects of placenta-plasma on pyorrhea alveolaris. Thirty patients (15 males and 15 females) aged from 18 to 47 were selected after physical examinations, and they have not any diseases except pyorrhea alveolaris and dental caries. 2cc of placenta-plasma were injected intramusculary twenty times every other day. Local and general treatment for this disease were not otherwise employed. The results obtained were as follows ; 1) After 20 injections of placenta-plasma, pus discharge and hemorrhage from gingival pockets decreased and became normal in all cases. 2) The pus pockets of 78 out of 266 teeth became 1mm or more shallower after 20 injections of placenta-plasma. There was no pus pocket that became deeper after treatment. 3) Swelling or edema, abnormal color of the gingiva and foetor ex ore decreased in all cases. 4) There was no remarkaable hyperplasia of margo alveolaris. 5) Before treatment, the percentages of alkaline phosphatase in neutrophilic leucocytes of patients were more than 80% in all cases and mean value was 90.0%. 6) After 10 injections of placenta-plasma, remarkable decrease of the percentage of alkaline phosphatase was observed. The mean 90.0 percentage of alkaline phosphatase became 50.8% (normal). 7) Observations of 26 cases at 0.5, 1.0, 1.5, 2, 3 years after treatment were, a) reformed conditions were continued in the above mentioned periods in 21 out of cases. 5 out of 26 cases recidivated slightly. b) the percentages of alkaline phosphatase were found normal in 18 cases, and those of other 8 cases were increased. c) the percentage of alkaline phosphatase in nentrophilic leucocytes in recidivated 5 cases were all increased. 8) Placenta-plasma was a promising and essential remedy for pyorrhea alveolaris.
