Abstract
More recently, it has been suggested that the residual monomer in cured composite restorative resins may cause an tissue reaction. The purpose of this investigation was to develop a method of measuring the residual monomer eluted into water from cured materials and to investigate the toxic effect of residual monomer upon Hela cells. The toxic effects upon these cells were examined by four residual monomers (ethylene glycol dimethacrylate, diethylene glycol dimethacrylate, triethylene glycol dimethacrylate and bisphenol A glycidyl methacrylate) eluted into water from cured materials. Among these dimethacrylates, bisphenol A glycidyl methacrylate produced the most unfavourable tissue reaction upon the cells.