Abstract
This is a case report of malignant hyperthermia. The patient was a 10 year-old male who was undergoing general anesthesia for cleft palate operation. He had experienced general anesthesia three times before, but there was no trouble. Anesthesia was induced with nitrous oxide-oxgen-halothane and trachea was intubated with two successive intr avenous injections of succinylcholine (SCC) 30 mg. After injection of SCC, rigidity of muscle, tachycardia (180/min) and ventricular arrythmia appeared. Arterial blood pressure fell to 70/30 mmHg. The rectal temperature rapidly increased from 36.8 ℃ to 39.0 ℃ within one hour. Anesthesia was changed to neuroleptanesthesia and the operation was completed as fast as possible. The patient was treated with infusion of iced saline, surface cooling with alcohol, controlled ventilation, correction for the acid base imbalance and administration of diuretics. The temperature returned to 36.9 ℃ in one hour. Post-operative creatine phosphokinase and lactate dehydrogenase level remained high for 12 days. The patient was discharged without sequelae on the 10th post-operative day.
