Two Tumors in the Oral Cavity of a Patient with von Recklinghausen's Disease : Neurofibroma and Pyogenic Granuloma

Abstract

We report here the two histopathologically different tumors in the oral cavity of a patient with von Recklinghausen's disease. The patient, a 59-year-old woman, visited our clinic with a chief complaint of two tumors at the hard palate mucosa and at the lower lingual gingiva. At first we diagnosed the case as neurofibromas, one of the oral manifestation of von Recklinghausen's disease, and then surgically removed the tumors by the same method under the local anesthesia. Histopathologically, the tumor at the hard palate was diagnosed as pyogenic granuloma with hyperplasia of capillary vessels. The other one at the lower lingual gingiva was diagnosed as neurofibroma, which was composed of Schwann cells, fibrilloblasts and collagen fibers. Over a 4 month period after surgical excision, neither recurrence nor malignant change has been observed.