Abstract
We evaluated influences of maturation, aging, and sex difference on laboratory blood chemistry examination in hospitalized patients at oral surgery divisions. Subjects included 4001 patients who were hospitalized from January 1992 to December 1997 at the First and Second Divisions of Oral Surgery, Kyushu Dental College Hospital, Kitakyushu, Japan. Serum concentrations of total cholesterol (TC), fasting blood sugar (FBS), blood urea nitrogen (BUN), and creatinine (Cr) were correlated positively with age, while calcium (Ca) and phosphate (P) concentrations were correlated inversely. The serum concentrations of total protein (TP), creatine phosphokinase (CPK), glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), γ- glutamyl transpeptidase (γ-GTP), TC, FBS, BUN, Cr, Fe, Cu, Ca, P, sodium (Na), and potassium (K) varied significantly with different age groups. GPT and γ-GTP were higher in middle-aged patients than in younger or older subjects. The concentrations of TC, FBS, and BUN were increased in older patients compared with younger patients, whereas TP, Ca, P were decreased with aging. Men had significantly higher concentrations of CPK, GOT, GPT, γ-GTP, BUN, Cr, FBS, Fe, Ca, and K, while TP, TC, Cu, Cl and P were higher in women. The present observations indicate that maturation, aging and sex difference clearly influence the serum concentrations of these blood chemistry examinations in hospitalized dental patients.
