結核菌ニ封スル猫ノ感受性ニ就テ

抄録

We have already reported twice previous l y that cat is not susceptible to human type of tubercle bacillus. In the present paper we wish to report on the study concerning the causes of this absence of susceptibility.
1. Fate of human type of tub e r cle bacilli inoculated in travenously to cat: When 5.0 mg of tubercle bacilli is intravenously inoculated the organisms remain in blood for a certain period of time, but disappear gradually. No tuberculous changes are, however, produced in liver, lung, spleen, kidney and lymphatic glands.
2. Bactericidal action of serum and growth inhibito r y action of whole blood of cat: Serum of normal cat has no bactericidal action, nor whole blood inhibitory action of growth of the organisms.
3. Phagocy t o sis: Phagocytic test according to the Ohtani's method showed 30 to 37% for human type and 1 to 3% for bovine type.
4. Relation of blocking and susceptibility: Injection of India ink or benzol reduces phagocytic action for human type to 1 to 9%. Injection of 5 mg of human type intravenously infects definitely in blocked cats.
Thus the mechanism of insusceptibility of cat for human type of tubercle bacillus appears to be due to the high phagocytic action of serum of normal cat. (Autoreferat.)