Reports have often been made on the decomposition of I-tyrosine by micro-organisms. It has been believed, however, that tubercle bacilli cannot decompose 1-tyrosine. The author could isolate tyrosol (phydroxyphenylethylalcohol) from the culture filtrate of the tubercle bacilli grown in Sauton's synthetic medium which contained 0.1 % I-tyrosine. While yeast fermentation gives a good yield of tyrosol from 1-tyrosine, the yield is small in the case of bacterial decomposition (Hirai, Miyazi) in which acid substance and amine were formed as the decomposition products. It is interesting to note that tubercle bacilli belong to mycobacterium and grow on the surface of ordinary liquid culture media like yeast.