P-ethylsulfonylbenzaldehyde tbiosemicarbazone(PE)に関する研究
(続報)人型結核菌H37Rv株及びH37RvR-PE株の酸素吸収に及ぼすPEの影響
1954 年 29 巻 8 号 p. 306-312
詳細
1954 年 29 巻 8 号 p. 306-312
Comparative studies were made on the influence of PE on the oxygen consumption of human type tubercle bacilli H37Rv and its variant PE 100γ/m1 resistant strain as well as on the same influence adding various substrates.
PE at a concentration of 60γ/ml revealed no significant influence on the oxygen consumption of resting tubercle bacilli. When a substrate such as glycerin, lactic acid, various kinds of amino acids, asparagin, benzoic acid or salicylic acid was added, PE inhibited the increase in the oxygen consumption of the susceptible strain, while, the consumption of the resistant strain received only a slight or no influence. Regarding other substrates, there was no significant difference between the susceptible strain and resistant one as to the inhibition of the increase in their oxygen consumption by PE.
