A case of pulmonary tuberculosis with positive culture of tuberculous bacilli in gastric lavage, complicated a swelling of 37 × 30 mm with slight tenderness at left supraclavicular area while underisoniazide therapy. Surgical extirpation was performed and resected material yielded positive cultureof Mycobacterium scrofulaceum and M. intracellulare. Histopathological finding revealed subcutaneous granulomatous lesion with multinuclear giant cells without caseous necrosis.