1986 年 61 巻 10 号 p. 509-514
Most of the reported cases of atypical mycobacteriosis are pulmonary narl discase, and generalized disseminated cases are very rare. We now report one case of generalized disseminated atypical mycobacteriosis caused by M. avium complex.
The patient was fernale of 49years of age. Her symptoms were general fatigue, lumbago, slight fever, anemia and liver dysfunction. Her blood sedimentation rate and CRP were abnormaly high. Judging from multiple osteal dissolution shown on her chest X-ray and chest CT film, and multiple accumulation in her osteal scintigraphic film, the case was diagnosed as osteal metastasis of malignant tumor on the beginning. The fever was considered to be caused by the tumor.
Antibiotics were given with no clinical result. Then predonisolone was administered, and was alleviated fever.
By culturing osteal tissue, M. avium complex was isolated, which led to a diagnosis of generalized disseminated atypical mycobacteriosis. Predonisolone was proved to be effective to improve general conditions.
Very low incidence of this type of disease makes diagnosis of the disease very difficult, and the report of this case isexpected to contribute to the early diagnosis of the disease.