2021 Volume 30 Issue 1 Pages 83-90
This study aimed to investigate the factors related to mild cognitive impairment (MCI) using baseline data from a cohort study that targeted older adult users of outpatient preventive long-term care services.
The study participants were registered in March 2017 and March 2018. Pure-tone audiometry, the Japanese version of the Montreal Cognitive Assessment (MoCA-J), and a self-administered questionnaire survey were conducted. The participants were classified into two groups based on MoCA-J scores : the MCI group (≤25 points) and the healthy group (≥26 points). A logistic model was used to adjust the effects of multiple factors, and the odds ratios (ORs) for the MCI were calculated.
Of the 296 registered participants, 217 (73%) had MCI. In total, 272 participants who fully answered the questionnaire were analyzed. The results indicated that the ORs for MCI increased with increases in age (65-79 vs. 80-84 years : OR=2.18 ; 65-79 vs. ≥85 years : OR=6.56). Participants with a history of diabetes had elevated ORs for MCI (OR=3.06). On the other hand, the ORs for MCI decreased in women (OR=0.46), those with a history of cerebrovascular disease (OR=0.30), those with a history of heart disease (OR=0.39), and those with high scores for instrumental activities of daily living (1-9 vs. 10-11 : OR=0.20 ; 1-9 vs. ≥12 : OR=0.37).
These results suggest that aging and diabetes are risk factors for MCI.