The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
THE RAT PANCREATIC LIPASE ACTIVITIES FOR TRIGLYCERIDE HYDROLYSIS
YASUMASA MAJIMA
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1970 年 19 巻 1 号 p. 21-26

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Six triglycerides consisting of oleic and palmitic acid labelled with 14C were subjected to hydrolysis in vitro by rat pancreatic lipase and the radioisotope activity of the monoglyceride produced was determined. Comparison with un-hydrolyzed triglycerides was accomplished. Results show the partial exchange of long chain triglyceride was found to take place not only at the 1.3 position, but also preferentially at the position of the unsaturated fatty acid. The possibility of the coexistence of 2 kinds of rat pancreatic lipase, one changing triglycerides to diglycerides and the other changing the diglyceride to a monoglyceride was suggested.
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