The Kitakanto Medical Journal
Online ISSN : 1881-1191
Print ISSN : 1343-2826
ISSN-L : 1343-2826
CASE REPORT
A Case of Advanced Gastric Cancer with Liver Metastases Resected Successfully after S-1+CDDP Combination Chemotherapy
Masaaki AraiRyo OchiaiKeitaro HiraiYutaka SunoseHideaki YokooIzumi Takeyoshi
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2011 Volume 61 Issue 4 Pages 519-524

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Abstract
A 63-year-old male presented with abdominal discomfort. Gastrointestinal endoscopy showed advanced gastric cancer type 2, which was diagnosed as moderate to poorly differentiated adenocarcinoma. Computed tomography (CT) showed a solitary liver metastasis about 5cm in diameter in the left lobe. The patient was treated with oral S-1, 80mg/m2/d for 21 d, followed by a 14-d rest, and cisplatin (CDDP), 60mg/m2, on day 8. The dose of S-1 and CDDP was reduced to 80% after one course because of side effects. After seven courses of treatment, CT and magnetic resonance imaging showed reduction of the liver metastasis to 2 cm in diameter in the lateral segment. A distal gastrectomy, lymph node dissection, and hepatic lateral segment resection were performed. Five months postoperatively, the patient is doing well and shows no sign of recurrence.
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© 2011 The Kitakanto Medical Society
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