2026 Volume 76 Issue 3 Pages 265-268
The patient was a 40-year-old woman who had been undergoing irregular cervical cancer screenings at our clinic since she was 21 years old. At the age of 34, she was found to have a (Negative for Intraepithelial Lesion or Malignancy) NILM cytology result and was positive for (human papilloma virus) HPV type 16 during a city-run cervical cancer screening program, and was followed up at our clinic. Due to the HPV type 16 positivity, her cytology results repeatedly showed NILM, but she continued to be followed up with cytology tests. Approximately six years after the initial diagnosis, at the age of 40, an increase in dysplasia was observed, progressing to (High-grade Squamous Intraepithelial Lesion) HSIL. This case suggests that even if cytology is normal, a positive HPV type 16 result should warrant observation.
