Abstract
This report deals with a autopsy case of Hodgkin's sarcoma in a 7 years girl. Principal clinical findings are swelling of lymphonodules around the neck and splenomegaly. In the peripheral blood anemia and remarkable leucocytosis contained a small number of myeloblasts and a great deal of the atypical monocytoid cell (Hodgkin's cell) are noticed.
Pathoanatomical finding :
1. Swelling of lymphonociules in the whole body and the thyroid gland.
2. Metastatic tumor formation in the heart, the lungs, the pleura, the kidney, the pancreas and the diaphragm.
3. Splenomegaly with a curious porphyry-like appearance.
4. Atelectasis of the left lung and upward displase of the left diaphragm.
5. Pleural effusion (100cc) and ascites (300cc) etc.
Pathohistological finding :
Lymphatic tumor tissue is constituted very variously with the proliferous reticulum cell, Hodgkin's cell, Sternberg's giant cell, fibroblast, collagenic fiber, lymphocytes and coagulative necrosis. And then some part of proliferous reticulum cell is characterized by pleomrorphism and mitosis of the nucleus and infiltrated character. Therefore, it is considered that this lymphatic tumor belong to a type of the Hodgkin's sarcoma.
In the myeloid tissue, free enlarged reticulum cell (tumor cell) infiltrated diffusely and hematopoesis is held normality. Because we supposed that remarkable leucocytosis in the peripheral blood is due to the leukomoid reaction as a result of metastatic tumor formation in the myeloid tissue.
