STUDIES ON NEPHROLITHOTOMY UNDER REGIONAL HYPOTHERMIA
1984 Volume 34 Issue 2 Pages 107-125
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1984 Volume 34 Issue 2 Pages 107-125
The animal experiment clearly demonstrated that regional hypothermia protect the renal damage suffered from temporary renal ischemia, judging from both ATPase activity in microsomal fraction and O2 consumption in mitochondrial fraction in rabbit kidney.
34 patients with complicated nephrolithiasis were operated under regional renal hypothermia. The average renal ischemic time of hypothermia treated cases with complicated nephrolithiasis was 89.8 ± 35.2 minutes as compared to 40.4 ± 10.3 minutes in operated under normothermia, that is, the former is twice as long as the latter. Nevertheless, the postoperative recovery of renal function in hypothermia treated cases, checked with renogram and IVP, was the same as that in normothermia treated cases.
