A CASE OF SKULL BASE METASTASIS OF HEPATOCELLULAR CARCINOMA WITH AN INVOLUNTARY MOVEMENT OF THE EYEBALL

Abstract

Skull base metastasis of hepatocellular carcinoma is relatively rare, and especially rare when the chief complaint is involuntary movement of the eyeball. We reported a 60-year-old man whose first symptom was involuntary movement of the left eyeball. A tumor, 4 × 3 × 2 cm³, in the skull base was detected by magnetic resonance imaging and a partial resection was performed. The histological diagnosis was consistent with hepatocellular carcinoma. Tumors were detected in the liver by computed tomography and gallium scintigraphy. Therefore it was diagnosed as bone metastasis of hepatocellular carcinoma. Radiotherapy was directed to the skull base, liver and the other sites of bone metastasis. The symptoms were improved.