CLINICAL STUDIES ON THE THYROID

II. CARBOHYDRATE METABOLISM IN THYROID DISEASESS

Abstract

In patients with thyroid diseases, the oral glucose, intravenous glucose, epinephrine, and insulin tolerance test were performed.
Diminished glucose tolerance was observed in 3 of 8 patients with thyrotoxicosis, and diminished glycemic response to epinephrine in 3 of 5 patients with the same disease. The sesult became normal after euthyroidism was established by the treatment with mercatoimidazole or radioactive iodine (I¹³¹).
Diminished oral glucose tolerance was observed in 6 of 11 patients with subacute thyroiditis diminished glycemic response to epinephrine in 3 of 8 such patients, and abnormal response to insulin-induced hypoglycemia in 12 of 16 such patients. As the gland softned and finally restored the normal size, the test gradually tended to show the normal response.