Abstract
This paper deals with the subcellular distribution of RNA of the midgut of the silkworm sinfected with cytoplasmic-polyhedrosis virus. The results obtained are as follows:
1. When silkworm was infected with cytoplasmic-polyhedrosis virus, the ratio of RNA content in mitochondrial fraction of diseased midgut decreased markedly, in the soluble fraction, on the other hand, increased strikingly, without any detectable difference on both nuclear and microsomal fractions.
2. RNA of each fraction was analyzed chromatographically with methylated albumin column. In the nuclear, mitochondrial and microsomal fractions of diseased midgut, IPB-RNA occupied 16. 0, 8. 1 and 5. 3 per cent to the total RNA respectively. It is of interest that a component like IPB-RNA was observed in microsomal fraction of healthy midgut amounting to 7 per cent of the total RNA.
