Number of aciduric bacteria in a oral specimen from 213 persons, classified into 15 healthy, 11 calculous, 7 gum inflamatory, 10 pyorrhoeal, 35 carious, 17 caries restored, 22 bridge wearing, 30 denture wearing and 66 miscellaneous in combination of above two or three categories, was counted by the method by Onisi and Kondo. According to the general acceptance, it was agreed that average of lactobacillus count in a group of the same number of carious teeth increased proportionally to the damage of tooth, but individual irregularity was too large to estimate the actual destruction of tooth as well as increasing destruction within certain period. In average number, countings from calculous and pyorrhoea patients were lesser than those from healthy mouths, and on the contrary countings from both carious and denture wearing mouth were significantly abundant. The hygienic state in a mouth seemed to have some effect to elimination of this organism. As the resulst, it was stressed that Lactobacilli opportunistically grow in a mouth, once a favorable enviroment is established there in some way, and its numerical increase does not respond to immunological state of dental caries.