The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
GENETIC STUDIES ON HERPES SIMPLEX VIRUS I. RECOMBINATION BETWEEN PLAQUE MORPHOLOGY AND IDU (5-IODO2'-DEOXYURIDINE) RESISTANCE
SHIGERU YAMAMOTOHIDEFUMI KABUTA
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1973 年 20 巻 2 号 p. 87-93

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The recombination experiments were carried out with herpes simplex virus between markers of plaque morphology and IDU (5-iodo-2'-deoxyuridine) resistance. The results suggest the contribution of noninfectious particles to genetic interaction. Kinetic studies demonstrated that recombination event occurs at any time during virus growth. Two reciprocal recombinants were produced in equal numbers regardless of multiplicities of infection of virus parents. This fact may allow to interpret the recombination by simple crossing-over between chromosomes or DNAs.
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