Abstract
Tamm-Horsfall glycoprotein was assayed in the urines of 5 chronic glomerulonephritis, 5 nephrotic syndrome and 5 chronic renal insufficiency. Urine samples were divided into three groups ; the original urine, the filtered fraction and the supernatant fraction after centrifugation, and then the Tamm-Horsfall glycoprotein content was measured both biochemically and immunologically. The filtration procedure greatly reduced the Tamm-Horsfall glycoprotein content, while the centrifugation had little effect on its content in each of all renal diseases. And furthermore, the Tamm-Horsf all glycoprotein content was significantly higher in the urines of both nephrotic syndrome and chronic renal insufficiency than in the urine of chronic glomerulonephritis.
