Lupus Anticoagulant as a Risk Factor for Cerebral Infarction and Habitual Abortions

KATSUHIRO MIZOGUCHI; SHINICHI KAKISAKO; MASAMITSU TANAKA; HIDEKI YANO; TOMOMI SHIMIZU; YUHJI GONDOH; HIROSHI SHOJI; MASARO KAJI

doi:10.2739/kurumemedj.36.113

KATSUHIRO MIZOGUCHI, SHINICHI KAKISAKO, MASAMITSU TANAKA, HIDEKI YANO, TOMOMI SHIMIZU, YUHJI GONDOH, HIROSHI SHOJI, MASARO KAJI

著者情報

キーワード: lupus anticoagulant, thrombosis, cerebral infarction, habitual abortions, pulmonary infarction

ジャーナルフリー

1989 年 36 巻 3 号 p. 113-116

DOI https://doi.org/10.2739/kurumemedj.36.113

詳細

抄録

A case involving a 34-year-old female with a progressive hemiparesis is described. She had a history of repeated spontaneous abortions. The CT and magnetic resonance imaging (MRI) showed a multiple cerebral infarction. A ^99mTc perfusion lung scintigram demonstrated diffuse bilateral perfusion defects in the lungs. The presence of lupus anticoagulant (LA) was detected from the laboratory data and the thrombosis in the genital organ. The repeated abortions were probably due to thrombosis in the placental vessels caused by LA. High dose steroid therapy was effective in suppressing the LA activity and in preventing progression of the clinical symptoms.

責任著者(Corresponding author)

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