1986 Volume 17 Issue 4 Pages 569-575
A 60-year-old female with 7 years history of generalized sarcoidosis and betamethasone therapy developed apparent proteinuria and slight intermittent glucosuria with minor abnormalities of urinary sediments. Oral GTT showed NIDDM. Urinalysis, blood chemistry, serology, and lymphocyte subsets were suggestive of membranous glomerulonephritis with generalized sarcoidosis and steroid-induced hyperglycemia. She died from cardiac arrhythmia 13 years later after the diagnosis of sarcoidosis and autopsy finidings of the kidney revealed diabetic glomerulosclerosis without granulomatous lesions. Although both diabetes mellitus and sarcoidosis are fairly common diseases in America and Europe, no report of diabetic nephropathy has yet been described on a patient with sarcoidosis. Thus, we report the renal histopathology of this case with her clinical course and laboratory data in detail.
