JOURNAL OF THE KYORIN MEDICAL SOCIETY
Online ISSN : 1349-886X
Print ISSN : 0368-5829
ISSN-L : 0368-5829
Radiotherapy Combined with Intracavitary Irradiation for Uterine Cervical Cancer : Study of Survival Rate, Patterns of Recurrence and Complication
Junko KUSUDAYoshiyuki MIZUTANIAyako YOSHINOMakoto TAKAYAMAYoshiro FURUYARyoji TAKEI
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1994 Volume 25 Issue 3 Pages 439-447

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Abstract

Survival rates and patterns of recurrence in 137 patients with uterine cervical cancer were determined. These patients were treated by radiotherapy with high-dose rate intracavitary irradiation using remote afterloading system (RALS) at Kyorin university Hospital from Oct. 1987 to Dec. 1992. Age range was from 29 to 87 years. According to clinical staging of UICC, stage I, II, III, and IV were observed in 29, 62, 33, and 13 cases respectively. Cumulative 5-year survival rate of all cases was 72 %. Cumulative 5-year survival rates were 100 % for stage I, 81 % for stage II, 38 % for stage III, and 27 % for stage IV. Cumulative 5-year survival rates of the postoperative radiotherapy and radical radiotherapy groups were 75 % and 90 % respectively. There was significant difference of survival rates between the postoperative radiotherapy group and the radical radiotherapy group. As patterns of recurrence, extrapelvic metastasis was more frequent than local recurrence. In stages II and III, recurrent patterns were extrapelvic metastasis in most cases. Of 18 cases with extrapelvic metastasis, there were 10 cases of paraaortic lymphnode metastasis. With increase in the control rate of parraortic lymphnode metastasis, survival rate of patients with uterine cervical cancer increased. Four of 5 cases with local recurrence controled by intracavitary irradiation is effective for local recurrence control. Rectal and bladder complications following radiotherapy were observed in 25 cases. However, all cases with complication after radiotherapy were treated conservatively, excluded 1 case (vasicorectal fistula).

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© 1994 by The Kyorin Medical Society
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