喉頭サルコイドーシスの一例

抄録

Sarcoidosis is a systemic disease characterized by granulomatous inflammation which may arise in many organ systems. Sarcoidosis of the larynx, however, is extremely rare. In this report a case of sarcoidosis affecting the right vocal fold is presented. A 47-year-old female had complained of hoarseness and sore throat during swallowing. Indirect and direct laryngoscopies demonstrated a diffuse swelling extending from the right vocal fold to the false vocal fold. The epiglottis and arytenoid were intact. Biopsy specimens obtained from the right vocal fold showed non-caseous granuloma with Langhans type giant cells. In some Langhans type giant cells asteroid bodies were observed. She was treated with oral medication of predonisolone and relieved from the hoarseness.