抄録
By using an image analyzing system, we evaluated the pattern of glandular tissue appearance in developing human infant larynges. The distribution of serous type glandular tissues was detected by staining with antiserum to S-100 protein and analyzed using an image binarization procedure (SPICCA II). The area occupied by glandular acini in the mucosa increased dramatically in older babies compared to the findings in younger neonates. The ratio of serous-type glands to mucous type glands was also determined by analyzing the binary image. The use of this new procedure is expected to facilitate immunopathologic studies of diseases of human infant larynx.
