2022 年 34 巻 3 号 p. 80-95
Ventricular assist device is used to treat end-stage severe heart failure. Rotary blood pumps which are widely used today, it has not pulsatile flow. On the other hand, many pulsatile pumps are installed outside the body through skin penetrations. In addition, implantable blood pumps are required a percutaneous penetration for energy transmission. Therefore, we have been developed a pulsatile ventricular assist device that can be driven percutaneously by applying magnetic coupling technology. aIn this study, we examined transcutaneous driving test during implantation and hemodynamic evaluation in animal experiments by using goat. As a result, our device had been achieved totally implanted in the subcutaneous and provided beating assistance without any percutaneous penetration. Although there was a limit to the mis-coupling of the magnets, the pump output was confirmed for blood pressure support. Our findings suggested that this system will be one candidate for cardiovascular support in the future.
