The Substructure of the Photodynamic Therapy by the Photosensitizer Talaporfin (Reza Flynn)

Abstract

Talaporfin is a photosensitizer of the molecular weight 799.73. We can check the lesion by observing fluorescence using the endoscopes image and fluorescence spectrum equipment. We introduce angioscope fluorescent image analysis equipment into an abdominal aorta with a hyperlipidemia rabbit, and are accumulated Talaporfin on the inner arteriosclerosis was observed. The arteriosclerosis part of the coronary arteries and its tip arteriole excited Talaporfin by 405 nm, and has observed it as a fluorescent image from the surface outside the heart. By the infrared spectrum, we observed the process to which arteriosclerosis is expanded. As a result, absorption peaks of arteriosclerosis at the ester and fatty acid increased and the ratio of the peak was 0.30. The (C=O) absorption peak of the cholesterol ester of arteriosclerosis was decreasing by the photodynamic therapy. The photodynamic therapy of the arteriosclerosis enabled target to observe spectra of ester. It seems that this observation can advance one big step towards the 21st century