2007 Volume 35 Issue 8 Pages 519-522
Photodynamic Diagnoses (PDD) are commonly applied in clinical and basic research areas. A conventional PDD with the maximal absorption wavelength of a photo sensitizer accumulated in the tumor tissue reveals its location. In this study, we evaluated the tissue transmittance of the lasers of two different wavelengths, 405 and 664 nm. These are the maximal absorption wavelengths of Talaporfin Sodium and appeared at different penetration depths in the tumor tissue. When these two wavelength lasers were irradiated to the tissue, different fluorescent intensities were obtained. From these different intensities and the different penetration depths of the lasers, the depth of the tumor's location is clarified.
