抄録
We compared the effi cacies of photodynamic therapy (PDT) with a light-emitting diode (LED) at the
green or red wavelength region using a computational simulation model with the Monte Carlo method
and a theoretical estimation based on quantum chemistry. The amount of singlet oxygen produced by a
green or red LED was comparable with that produced by a green or red laser, respectively, and that
produced by the green LED with a peak emission wavelength of 515 nm exceeded that produced by the
red LED with a peak emission wavelength of 629 nm within a depth of about 2 mm. We infer that PDT
with a green LED is effective for cancers localized around such tissue surfaces as the intraepithelial
carcinoma of the bladder.
