Abstract
Optical measurements, which play a pivotal role in scientific, industrial, and medical fields, utilize diverse
optical properties. The development of optical-frequency-comb is a breakthrough in such optical
measurements. Optical-frequency-combs exhibit highly time-controlled pulse trains or meticulously
structured multispectral arrays of narrow optical frequency modes and offer remarkable accuracy and
precision. The controlled nature of optical-frequency-combs allows for highly accurate and precise optical
measurements, contributing to a broad spectrum of precision measurements. This review describes
the potential applications of optical-frequency-combs in optical microscopy. Integrating them into optical
microscopy introduces a novel approach that leverages the temporal and spectral properties, including
methods for extracting various light parameters through the time characteristics of optical-frequency-
combs and superimposing spatial information on each comb mode by utilizing their spectral characteristics.
Optical microscopy with optical-frequency-combs is a novel means of optical measurement
with broad applicability across various fields.
