Ultraviolet laser ablation of lipid has been investigated. ArF, KrF and XeC1 excimer lasers have been adopted in this study. A fresh suet is used as the tissue sample. Ablation capability of the KrF laser was remarkably better than that of other lasers. Ablation threshold of the ArF laser was lower by six hold than that of the KrF laser. The ArF laser, however, did not efficiently ablate the suet at high-energy fluence due to spallation. The XeCI laser had poor ablation capability. These results suggest that the KrF laser is the most suitable laser for ablation of lipid.