EXPERIMENTAL STUDIES ON VIRICIDAL ACTIVITY OF NITROGEN MUSTARD DERIVATIVES ON VARIOUS ANIMAL VIRUSES

MASAKATSU GOTO; SHINYA OKUBO; KATSUHIKO SUZUNO; SADAO KIMURA; MORIZO ISHIDATE; YOSHIO SAKURAI

doi:10.1111/j.1348-0421.1957.tb00034.x

MASAKATSU GOTO, SHINYA OKUBO, KATSUHIKO SUZUNO, SADAO KIMURA, MORIZO ISHIDATE, YOSHIO SAKURAI

著者情報

ジャーナルフリー

1957 年 1 巻 4 号 p. 347-354

DOI https://doi.org/10.1111/j.1348-0421.1957.tb00034.x

詳細

抄録

1) The action of 36 (β-chloroethyl) amine derivatives on various animal viruses was studied.
2) Benzyl-bis-(β-chloroethyl) amine and its N-oxide are most effective in inactivating fixed rabies virus and vaccinia virus. Tris-(β-chloroethyl) amine is also effective against influenza virus.
3) The mechanism of the antiviral activity of these compounds appears to be prophylactic.

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