Japanese Journal of Microbiology
Print ISSN : 0021-5139
STUDIES ON EPIDEMIC DIARRHEA OF WEANLING IN JAPAN (ITO'S PSEUDOCHOLERA INFANTUM) ISOLATION AND IDENTIFICATION OF VIRUS FROM THE FECES OR SERUM OF PATIENTS
SEIJI ARAKAWATAKENORI SATOISAMU KONDOTIAKI KANEKOTOMIO SEKITERUJI SHINOZUKATAKAO SAKATAJUSHICHIRO NAITO
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1957 Volume 1 Issue 4 Pages 415-422

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Abstract

1. A new virus from the pseudocholera infantum patients was successfully isolated and fixed to the mouse. Cultivation in fertile chicken eggs also serves the same purpose.
2. The fixed virus obtained is not neutralized by the serum of patients immediately after the onset of the disease. But following the course of illness, neutralization increases gradually. The same tendency is observed also in the complement fixation test conducted with the sera of both patients and their mothers and the antigen from the fixed virus. Under these circumstances, the production of antibody which responds to this virus is recognized earlier in the mothers than in the infants. This fact seems to suggest the occurrence of inapparent infection of this disease in adults.

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