Japanese Journal of Microbiology
Print ISSN : 0021-5139
Heat-Labile Virus-Inhibiting Factor or Interferon Induced by Virus
Nobutoshi MAEHARAYasuiti NAGANO
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1970 年 14 巻 4 号 p. 257-260

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抄録
Stability to heat and acid of the virus-inhibiting factor (IF) or interferon induced by viruses is generally accepted. Published data suggest, however, a heterogeneity in the virus-induced IFs in their physico-chemical and biological properties. The present work shows that the IF activity of rabbit serum collected 2 hr after intravenous inoculation with Newcastle disease virus is as labile as E. coli endotoxin-induced IF when heated at 56C or dialysed at pH 2, whereas the serum-IF at 6 hr is significantly more stable.
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