抄録
Stability to heat and acid of the virus-inhibiting factor (IF) or interferon induced by viruses is generally accepted. Published data suggest, however, a heterogeneity in the virus-induced IFs in their physico-chemical and biological properties. The present work shows that the IF activity of rabbit serum collected 2 hr after intravenous inoculation with Newcastle disease virus is as labile as E. coli endotoxin-induced IF when heated at 56C or dialysed at pH 2, whereas the serum-IF at 6 hr is significantly more stable.