Japanese Journal of Microbiology
Print ISSN : 0021-5139
A Soluble Antigen of Infectious Bronchitis Virus
Takeshi HIRONAOTaketsugu MASUIYukio BITO
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ジャーナル フリー

1970 年 14 巻 6 号 p. 495-500

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抄録
A soluble antigen of infectious bronchitis virus was detectable by immunodiffusion in chorioallantoic membranes of embryonating chicken eggs 12 hr after infection. The antigen was inactivated by heating at 60 C for 10 min, and by digestion with trypsin, and was not destroyed by DNase or RNase. The antigen was partially inactivated by treatment with acetone and chloroform but only a slight or no inactivation was observed by treatment with ether. The antigen was partially precipitated with ammonium sulfate. In sucrose gradient centrifugation the antigen sedimented slightly faster than chicken hemoglobin.
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