MICROBIOLOGY and IMMUNOLOGY
Online ISSN : 1348-0421
Print ISSN : 0385-5600
ISSN-L : 0385-5600
Increased Nitroblue Tetrazolium Dye Reduction by Human Neutrophils Stimulated by Interferon In Vitro
Chin-Bin PAKJiro IMANISHITsunataro KISHIDAAkio MATSUO
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1980 年 24 巻 8 号 p. 717-723

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Human leukocyte interferon enhanced nitroblue tetrazolium dye (NBT) reduction by human neutrophils (PMNs). Increase in NBT reduction paralleled increase in interferon dose. When human leukocyte interferon was heated to 60 C or 80 C for 30 min, both the antiviral activity and the effect on NBT reduction decreased. Human leukocyte interferon neutralized with anti-human leukocyte interferon serum showed no effect on NBT reduction. A human fibroblast interferon preparation also enhanced NBT reduction. The species dependency of interferon was shown in NBT reduction as well as in antiviral activity.
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© Center for Academic Publications Japan
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