MICROBIOLOGY and IMMUNOLOGY
Online ISSN : 1348-0421
Print ISSN : 0385-5600
ISSN-L : 0385-5600
No Involvement of Bovine Leukemia Virus in Sporadic Bovine Lymphosarcoma
Yasuki OGAWANoriyuki SAGATAJunko TSUZUKU-KAWAMURAMisao ONUMAHisao IZAWAYoji IKAWA
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1986 年 30 巻 7 号 p. 697-701

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Using various portions of a molecularly cloned bovine leukemia virus (BLV) DNA as probes, the possible integration of a BLV genome or a BLV-related sequence into the chromosomal DNA of sporadic bovine leukosis (SBL) tumor cells was investigated by Southern blotting analysis. Under stringent as well as nonstringent conditions of hybridization, neither BLV nor BLV-related sequence specific to SBL DNAs was detected in any SBL tumor examined. These results provide conclusive evidence for lack of the relation of BLV or a BLV-related agent to SBL.
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