Nephrotic syndrome is known to cause hypercoagulation due to various factors. Steroid therapy is considered the main treatment for nephrotic syndrome. However, this can increase the risk of developing venous thromboembolism, prompting caution in its use. Here, we report a case of venous thromboembolism in a 13-year-old girl with acute renal failure. This developed during catheter insertion into the right internal jugular vein for hemodialysis. We initiated direct oral anticoagulant therapy. Ultrasound was used to monitor the jugular vein. Throughout the course of treatment, the venous thrombosis gradually disappeared. This study highlights the importance of considering prophylactic anticoagulant therapy in patients with nephrotic syndrome who have an increased risk of venous thromboembolism during central venous catheter placement.
