抄録
A new method is proposed for elimination of artifacts appearing in deconvolution of electrospray ionization mass spectra, where two algorithms, a partial correlation method (PCM) and a sub-harmonic artifact removal filter (SHARF), are used. In addition to the elimination of artifacts, the former algorithm removes influence of singly charged ions generated from contamination in a sample, while the latter algorithm removes influence of background noises and baseline offsets in a measured spectrum. The proposed method results in supplying the deconvoluted spectra free from artifacts with good signal-to-noise ratios and without distortion on peak shapes. Applications to some bio-molecules lead to the conclusion that our method is especially useful for analyses of their mixture samples, which show complicated mass spectra.
